Pores in the Wall

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Pores in the Wall

Address correspondence to Shoichiro Tsukita, M.D., Ph.D., Department of Cell Biology, Faculty of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan. Tel.: 81-75-753-4372. Fax: 81-75-753-4660. E-mail:htsukita @mfour.med.kyoto-u.ac.jp 1 Abbreviations used in this paper: CPE, Clostridium perfringens enterotoxin; TJ, tight junction. In vertebrates, tight junctions (TJs) 1 play a central ro...

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Pores in the Wall: Claudins Constitute Tight Junction Strands Containing Aqueous Pores

Address correspondence to Shoichiro Tsukita, M.D., Ph.D., Department of Cell Biology, Faculty of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan. Tel.: 81-75-753-4372. Fax: 81-75-753-4660. E-mail:htsukita @mfour.med.kyoto-u.ac.jp 1 Abbreviations used in this paper: CPE, Clostridium perfringens enterotoxin; TJ, tight junction. In vertebrates, tight junctions (TJs) 1 play a central ro...

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Wall-mediated self-diffusion in slit and cylindrical pores.

Analytical and numerical simulation studies are performed on the diffusion of simple fluids in both thin slits and long cylindrical pores. In the region of large Knudsen numbers, where the wall-particle collisions outnumber the intermolecular collisions, we obtain analytical results for the self-diffusion coefficients for both slit and cylindrical pore shapes. The results show anomalous behavio...

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Do large pores in the glomerular capillary wall account for albuminuria in nephrotic states?

Albuminuria in nephrotic states is thought to arise from the formation of large pores in the glomerular capillary wall as large hydrodynamic probes, like Ficoll, have increased fractional clearance. In the present study, we tested for large pore formation in a novel manner. We accounted for the rates of plasma elimination as determined for tritium-labeled tracers of uncharged polydisperse Ficol...

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Modulation of outflow resistance by the pores of the inner wall endothelium.

The juxtacanalicular connective tissue (JCT) is widely believed to generate the bulk of aqueous humor outflow resistance, while the pores of the inner wall endothelium are thought to generate at most 10% of this resistance in humans. However, the hydrodynamic interaction of these two components of the aqueous outflow system, which arises because of their spatial proximity, has only recently bee...

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ژورنال

عنوان ژورنال: Journal of Cell Biology

سال: 2000

ISSN: 0021-9525,1540-8140

DOI: 10.1083/jcb.149.1.13